Vetenskapliga publikationer från innovationsprojekt

Preventing pressure ulcers in emergency departments

Stanberry, Benedict; Lahti, Nina; Kevin, Carolin and Delin, Jenny. Preventing pressure ulcers in emergency departments: four simple and effective nurse-led changes. 2021.  Emergency Nurse.

Digitala beslutsstöd vid prostatacancer

Projekt inom End-to-ENd-Oncology, ett av fem fokusområden för Karolinskas innovationspartnerskap med Philips. Arbetet sker i global kontext tillsammans med flertalet universitet, vårdgivare och andra aktörer.

1. Ronmar. Erik; Hoffmann, Ralf; Skokic, Viktor; de Klerk-Starmans, Maud; Jaderling, Fredrik; Vos, Pieter; C. W. Gayet, Maudy; Hofstraat, Hans; Janssen, Marco; Akre, Olof; and Vincent, Per Henrik. 2022. Effect of digital-enabled multidisciplinary therapy conferences on efficiency and quality of the decision making in prostate cancer care. BMJ Health & Care Informatics.

Augmented reality guidar kirurgen i realtid

Ett projekt inom Minimally Invasive Surgery, ett av fem fokusområden för Karolinskas innovationspartnerskap med Philips. Arbetet sker i global kontext tillsammans med flertalet universitet, vårdgivare och andra aktörer.

1. Elmi-Terander, Adrian; Skulason, Halldor; Söderman, Michael; Racadio, John; Homan, Robert; Babic, Drazenko; van der Vaart, Nijs och Nachabe, Rami. 2016. Surgical Navigation Technology Based on Augmented Reality and Integrated 3D Intraoperative Imaging: A Spine Cadaveric Feasibility and Accuracy Study. Spine.
2. Elmi-Terander, Adrian; Nachabe, Rami; Skulason, Halldor; Pedersen, Kyrre; Söderman, Michael; Racadio, John; Babic, Drazenko; Gerdhem, Paul och Edström, Erik. 2018. Feasibility and Accuracy of Thoracolumbar Minimally Invasive Pedicle Screw Placement with Augmented Reality Navigation Technology. Spine.
3. Elmi-Terander, Adrian; Burström, Gustav; Nachabe, Rami; Skulason, Halldor; Pedersen, Kyrre; Fagerlund, Michael: Ståhl, Fredrik; Charalampidis, Anastasios; Söderman, Michael; Holmin, Staffan; Babic, Drazenko; Jenniskens, Inge; Edström, Erik och Gerdhem, Paul. 2019. Pedicle Screw Placement Using Augmented Reality Surgical Navigation With Intraoperative 3D Imaging: A First In-Human Prospective Cohort Study. Spine.
4. Burström, Gustav; Nachabe, Rami; Persson, Oscar; Edström, Erik och Elmi Terander, Adrian. 2019. Augmented and Virtual Reality Instrument Tracking for Minimally Invasive Spine Surgery: A Feasibility and Accuracy Study. Spine.
5. Burström, Gustav; Buerger, Christian; Hoppenbrouwers, Jurgen; Nachabe, Rami; Lorenz, Cristian; Babic, Drazenko; Homan, Robert; Racadio, John M.; Grass, Michael; Persson, Oscar; Edström, Erik och Elmi Terander, Adrian. 2019. Machine learning for automated 3-dimensional segmentation of the spine and suggested placement of pedicle screws based on intraoperative cone-beam computer tomography. Journal of Neurosurgery.
6. Edström, Erik; Burström, Gustav; Omar, Artur; Nachabe, Rami; Söderman, Michael; Persson, Oscar; Gerdhem, Paul och Elmi-Terander, Adrian. 2020. Augmented Reality Surgical Navigation in Spine Surgery to Minimize Staff Radiation Exposure. Spine.
7. Edström, Erik; Burström, Gustav; Nachabe, Rami; Gerdhem, Paul och Elmi Terander, Adrian. 2020. A Novel Augmented-Reality-Based Surgical Navigation System for Spine Surgery in a Hybrid Operating Room: Design, Workflow, and Clinical Applications. Operative Neurosurgery.
8. Elmi-Terander, Adrian; Burström, Gustav; Nachabé, Rami; Fagerlund Michael; Ståhl, Fredrik; Charalampidis, Anastasios; Edström, Erik och Gerdhem, Paul. 2020. Augmented reality navigation with intraoperative 3D imaging vs fluoroscopy-assisted free-hand surgery for spine fixation surgery: a matched-control study comparing accuracy. Nature.
9. Balicki, Marcin; Kyne, Sean; Toporek, Grzegorz; Holthuizen, Ronald; Homan, Robert; Popovic, Aleksandra; Burström, Gustav; Persson, Oscar; Edström, Erik; Elmi-Terander, Adrian; Patriciu, Alexandru. 2020. Design and Control of Image Guided Robot for Spine Surgery in Hybrid OR. The International Journal of Medical Robotics and Computer Assisted Surgery.
10. Burström, Gustav; Balicki, Marcin; Patriciu, Alexandru; Kyne, Sean; Popovic, Aleksandra; Holthuizen, Ronald; Homan, Robert; Skulason, Halldor; Persson, Oscar; Edström, Erik och Elmi-Terander, Adrian. 2020. Feasibility and accuracy of a robotic guidance system for navigated spine surgery in a hybrid operating room: a cadaver study. Nature. 
11. Manni, Francesca; Elmi-Terander, Adrian; Burström, Gustav; Persson, Oscar; Edström, Erik; Holthuizen, Ronald; Shan, Caifeng; Zinger, Svitlana; van der Sommen, Fons; and de With, Peter H. N. 2020. Towards Optical Imaging for Spine Tracking without Markers in Navigated Spine Surgery. (Special Issue Sensors for Biomedical Imaging). Sensors.
12. Manni, Francesca; van der Sommen, Fons; Zinger, Svitlana; Shan, Caifeng; Holthuizen,; Lai, Marco; Buström, Gustav; Hoveling, Richelle J. M.; Edström, Erik; Adrian Elmi-Terander, Ronald och de With, Peter H. N. 2020. Hyperspectral Imaging for Skin Feature Detection: Advances in Markerless Tracking for Spine Surgery. Applied Sciences.
13. Edström, Erik; Burström, Gustav; Persson, Oscar; Charalampidis, Anastasios; Nachabe, Rami; Gerdhem, Paul och Elmi-Terander, Adrian. 2020. Does Augmented Reality Navigation Increase Pedicle Screw Density Compared to Free-Hand Technique in Deformity Surgery? Single Surgeon Case Series of 44 Patients. Spine.
14. Burström, Gustav; Cewe, Paulina; Charalampidis, Anastasios; Nachabe, Rami; Söderman, Michael; Gerdhem, Paul; Elmi-Terander, Adrian och Edström, Erik. 2020. Intraoperative cone beam computed tomography is as reliable as conventional computed tomography for identification of pedicle screw breach in thoracolumbar spine surgery. European Radiology.
15. Burström, Gustav; Nachabe, Rami Homan, Robert; Hoppenbrouwers, Jurgen; Holthuizen, Ronald; Persson, Oscar; Edström, Erik och Elmi-Terander, Adrian. 2020. Frameless Patient Tracking With Adhesive Optical Skin Markers for Augmented Reality Surgical Navigation in Spine Surgery. Spine.
16. Manni, Francesca;Mamprin, Marco; Holthuizen, Ronald; Shan, Caifeng; Burström, Gustav; Elmi-Terander, Adrian; Edström, Erik; Zinger, Svitlana och de With, Peter H. N. 2021. Multi-View 3D Skin Feature Recognition and Localization for Patient Tracking in Spinal Surgery Applications. BioMedical Engineering OnLine 20, Article number: 6 (2021).
17. 2021. Specvial issue with focus on Virtual and Augmented Reality. Volume 51, Issue 2. Neurosurgical Focus. Jean, Walter; Elmi Terander, Adrian; Britz, Gavin B.; McIntyre, Cameron and DiMEco, Francesco (Eds.).
18. Cewe, Paulina; Vorbau, Robert; Omar, Artur; Elmi-Terander Erik Edström. 2021. Radiation distribution in a hybrid operating room, utilizing different X-ray imaging systems: investigations to minimize occupational exposure. British Medical Journal.

Smarta instrument – detekterar olika typer av vävnad under operation

Ett projekt inom Minimally Invasive Surgery, ett av fem fokusområden för Karolinskas innovationspartnerskap med Philips. Arbetet sker i global kontext tillsammans med flertalet universitet, vårdgivare och andra aktörer.

1. Swamy, Akash; Burström, Gustav; W Spliethoff, Jarich; Babic, Drazenko; Reich, Christian; Groen, Joanneke; Edström, Erik; Elmi Terander, Adrian; Racadio, JOhn M.; Dankelman, Jenny och Hendriks, Benno H. W. 2019. Diffuse reflectance spectroscopy, a potential optical sensing technology for the detection of cortical breaches during spinal screw placement. Journal of Biomedical Optics.
2. Swamy, Akash; Burström, Gustav; Spliethoff, Jarich W.; Babic, Drazenko; Ruschke, Stefan; Racadio, John M. ; Edström, Erik; Elmi Terander, Adrian; Dankelman, Jenny and Hendriks, Benno H. W. 2019. Validation of diffuse reflectance spectroscopy with magnetic resonance imaging for accurate vertebral bone fat fraBurström, Gustav; Swamy, Akash; Spliethoff, Jarich W,; Reich, Christian; Babic, Drazenco; Hendriks, Benno H. W.; Skulason, Halldor; Persson, Oscar; Elmi Terander, Adrian och Edström, Erik. 2019. Diffuse reflectance spectroscopy accurately identifies the pre-cortical zone to avoid breach in spinal fixation surgery. Biomedical Optics Express.
3. Swamy, Akash; Spliethoff, Jarich W.; Burström, Gustav; Babic, Drazenko; Reich, Christian; Groen, Joanneke; Edström, Erik; Elmi-Terander, Adrian; Racadio, John M.; Dankelman, Jenny och Hendriks, Benno H. W. 2020. Diffuse reflectance spectroscopy for breach detection during pedicle screw placement: a first in vivo investigation in a porcine model. Bimedical Engineering Onlie.

Smarta katetrar

Ett projekt inom Stroke, ett av fem fokusområden för Karolinskas innovationspartnerskap med Philips. Arbetet sker i global kontext tillsammans med flertalet universitet, vårdgivare och andra aktörer.

1. Skyrman, S.; Burström, G.; Aspegren, O.; Lucassen, G.; Elmi-Terander, A.; Edström, E. och Andersson, T. 2021. Identifying clot composition using intravascular diffuse reflectance spectroscopy in a porcine model of endovascular thrombectomy. Journal of NeuroInterventional Surgery.

Endoscope tracking 

Ett projekt inom Minimally Invasive Surgery, ett av fem fokusområden för Karolinskas innovationspartnerskap med Philips. Arbetet sker i global kontext tillsammans med flertalet universitet, vårdgivare och andra aktörer.

1. Lai, Marco; Shan, Caifeng; Babic, Drazenko; Homan, Robert; Elmi Terander, Adrian; Edstrom, Erik; Persson, Oscar; Burstrom, Gustav; de With, Peter H. N. . 2019. Image fusion on the endoscopic view for endo-nasal skull-base surgery. SPIE Medical Imaging.
2. Lai, Marco; Skyrman, Simon; Shan, Caifeng; Babic, Drazenko; Homan, Robert; Edström, Erik; Persson, Oscar; Burström, Gustav; Elmi-Terander, Adrian; Hendriks, Benno H. W. och de With, Peter H. N. 2020. Fusion of augmented reality imaging with the endoscopic view for endonasal skull base surgery; a novel application for surgical navigation based on intraoperative cone beam computed tomography and optical trackin. PLoS One.

Stroke – när varje sekund räknas 

Stroke är ett av fem fokusområden inom Karolinskas innovationspartnerskap med Philips. Arbetet sker i global kontext tillsammans med flertalet universitet, vårdgivare och andra aktörer.

1. Simon, M.; Engel, K. J.; Menser, B.I Ruetten, W.; Thran, A. och Schaefer, D. 2020. Physical image simulation of human brain in case of acute stroke. Medical Imaging.
2. Engel, K. J.; Menser, B.; Rohr, P.; Ruetten, W., Simon, M. och Thran, A. 2020. Dual layer x-ray detector simulation. Medical Imaging.
3. Moreira, Tiago; Furnica, Alexander; Daemen, Elke; Mazya, Michael V.; Sjöstrand, Christina; Kaijser, Magnus and van Loenen, Evert. 2021. Staff and Facility Utilization in Direct Patient Transfer to the Comprehensive Stroke Center: Testing a Real-Time Location System for Automatic Patient Pathway Characterization. Frontiers in Neurology.

VRI Proaktiv – nya IT- och AI-stöd för att förebygga vårdrelaterade infektioner

Ett nationellt samarbete mellan universitetssjukhus, universitet, företag och myndigheter.

1. Karlsson Valik, John; Tanushi, Hideyuki; Müllersdorf, Kajsa; Ternhag, Anders; Aufwerber, Ewa; Färnert, Anna; Lause Mogensen, Mads; Pickering, Brian; Dalianis, Hercules; Henriksson, Aron; Herasevich, Vitaly och Nauclér, Pontus. 2020. Validation of automated sepsis surveillance based on the Sepsis-3 clinical criteria against physician record review in a general hospital population: observational study using electronic health records data. British Medical Journal.

Videobesök 

Samarbete mellan Karolinska Institutet och Karolinska Universitetssjukhuset.

1. Sturesson, Linda och Groth, Kristina. 2018. Effects of the Digital Transformation: Qualitative Study on the Disturbances and Limitations of Using Video Visits in Outpatient Care. Journal of Medical Internet Research.
2. Sturesson, Linda och Groth, Kristina. 2018. Clinicians’ Selection Criteria for Video Visits in Outpatient Care: Qualitative Study. Journal of Medical Internet Research. 

ERCP – kirurger vägleder andra kirurger på distans

Innovationspartnerskap mellan Karolinska Universitetssjukhuset och Boston Scientific. Även samarbete med Karolinska Institutet, Kungliga tekniska högskolan och Malmö universitet.

1. Påhlsson, H.-I. Påhlsson; Groth K.; Permert J.; Swahn F.; Löhr M.;, Enochsson L.; Lundell L. och Arnelo U. 2013. Telemedicine: an important aid to perform high-quality endoscopic retrograde cholangio- pancreatography in low-volume centers. Journal of Endoscopy.
2. Brinne Roos, J.; Bergenzaum, P.; Groth K.; Lundell, L. och Arnelo U. 2019. Telepresence-teleguidance to facilitate training and quality assurance in ERCP. A health economic modeling approach. Endoscopy International Open.
3. Aminoff, Hedvig; Meijer, Sebastiaan; Arnelo, Urban och Frennert, Susanne. 2021. Telemedicine for Remote Surgical Guidance in Endoscopic Retrograde Cholangiopancreatography: Mixed Methods Study of Practitioner Attitudes. JMIR Formative Research.

Telemedicinsk hemtitrering – utprovning av läkemedel mot Parkinson på distans (i hemmet)

Ett samabrete mellan Karolinska UNiversitetssjukhuset och AbbVie.

1. Willows, T.; Dizdar, N.; Nyholm, D.; Widner, H.; Grenholm, P.; Schmiauke, U.; Urbom, A.; Groth, K.; Larsson, J.; Permert, J. och Kjellander, S. 2017. Initiation of levodopa-carbidopa intestinal gel infusion using telemedicine (video communication system) facilitates efficient and safe home titration in patients with advanced Parkinson's disease. Journal of Parkinson's Disease.

För bättre underlag till multidisciplinära beslutskonferenser

Innovationsamarbete mellan Karolinska Institutet, Kungliga tekniska högskolan och Karolinska Universitetssjukhuset, för att utforska möjligheter att genom visualisering och interaktion förbättra underlag för diskussion och beslutsfattande under multidisciplinära konferenser.

1. Groth, K.; Olin, K.; Gran, O. och Permert, J. 2008. The role of technology in video-mediated consensus meetings. Journal of telemedicine and e-health, 14 (7).
2. Frykholm, O. och Groth, K. 2011. References to Personal Experiences and Scientific Evidence during Medical Multi-Disciplinary Team Meetings. Journal of Behaviour and Information Technology, 30 (4), special issue on Medical Team Meetings.
3. Kane, B.; Groth, K. och Randall, D. 2011. Medical Team Meetings: Utilising technology to enhance communication, collaboration and decision-making. Special issue on Medical Team Meetings. In Journal of Behaviour and Information Technology 30 (4).
4. Scholl, J. och Groth, K. 2012. Of Organization, Device and Context: Interruptions from Mobile Communication in Highly Specialized Care. Interacting with Computers, Elsevier.
5. Groth, K. och Frykholm, O. F2014. Building Relationships: HCI Researchers at a Gastro Surgical Department. In Fieldwork for Healthcare: Case Studies Investigating Human Factors in Computing Systems. Furniss, D., O’Kane, A. A., Randell, R., Taneva, S., Mentis, H. & Blandford, A. (Eds). Morgan & Claypool Publishers.
6. Taneva, S.; O’Kane, A.; Ratwani, E.; Hilligoss, B.; Thieme, A. och Groth, K. 2015. Establishing and Maintaining Relationships in Healthcare Fields. In Furniss, D., Randell, R., O’Kane, A., Taneva, S., Mentis, H. & Blandford, A. (Eds.) Fieldwork in Healthcare: Guidance for investigating human factors in computing systems [Volume2]. Morgan & Claypool Publishers.